
Metabolism, Mitochondria, and Measured Recovery: Dr. Rick Cohen’s PureClean Performance Method
Precision metabolic strategy linking amino acids, breath-hold conditioning, mitochondrial maintenance, deuterium-depleted water, structured water theory, and HRV-guided recovery.
Amino Acids for Performance
Performance rises when amino acid delivery matches real metabolic load rather than generic protein quotas. Align intake with training density, autonomic state, and digestive tolerance so contractile proteins, neurotransmitters, and mitochondrial enzymes receive substrate when the system can use it.
Essential amino acids are the limiting building blocks for repair and neural drive. Branched-chain amino acids influence central fatigue only when balanced against the full essential profile and adequate electrolytes. Glycine and proline support collagen turnover and fascia integrity, improving force transmission and movement economy. The objective is coherent nitrogen handling, not maximal grams.
Timing with signals
Place amino acid intake where readiness indicators show capacity to adapt. Strong breath-hold performance, stable morning pH, and favorable orthostatic heart-rate response imply better utilization. Under sympathetic load or poor sleep, shift to digestible essential blends and support with electrolytes and whole vitamin C complexes that assist collagen and copper dynamics.
Breath-Hold Training & Sleep Apnea
Breath-hold training conditions chemoreflex sensitivity and CO₂ tolerance, two levers that influence airway stability and autonomic balance during sleep. Sets create controlled hypoxia and hypercapnia without provoking stress spillover. Track SpO₂ nadirs, recovery kinetics, and effort to anchor progression.
For sleep apnea the aim is steady improvement in tolerance, nasal airflow discipline, and parasympathetic rebound. Mechanical supports such as nasal dilators and careful mouth-taping can assist while breath-hold practice recalibrates the internal control loop governing ventilation and arousal thresholds.
Measurable change
When breath-hold indexes rise and effort smooths across sets, nocturnal snoring burden often falls. Pair training with temperature regulation and light hygiene so circadian timing supports the same autonomic direction.
Mitochondrial Health and Aging
Aging appears as declining flexibility of the mitochondrial network. The daily readout is simple: energy either flows with low friction, or it does not. Terrain markers such as breath-hold variability, HRV patterns, morning urine pH trends after bicarbonate titration, and orthostatic heart-rate reveal whether redox and acid–base balance support efficient ATP production.
Correctives follow sequence. Stabilize sleep and light. Replete electrolytes and optimize RBC magnesium rather than relying on superficial serum values. Favor whole-complex vitamin C when connective tissue and copper handling matter. Use amino acids with intent, and add movement that pushes CO₂ tolerance without excessive catecholamine activation.
Deuterium-Depleted Water
Hydrogen isotope load influences mitochondrial nanomotor behavior and metabolic signaling. Deuterium-depleted water (DDW) reduces that load and can shift how the system handles energy and repair, particularly when baseline terrain is already optimized for light, sleep, and mineral status.
DDW is introduced contextually in the PureClean framework and monitored against readiness metrics rather than used as a stand-alone cure. Track breath-hold performance, morning pH response, and HRV trends when experimenting with DDW to determine individual responsiveness.
Electronic Biology: Szent-Györgyi, Gilbert Ling, Structured Water and MRI
here is the content I am not usually interested in dipping into the Jack Kruze world as output is more important but I could never get my head around the Szent-Györgyi Gilbert Ling connection until now. This is geeky cool and so classic of our current molecular paradigm. For decades, Szent-Györgyi has been remembered for vitamin C as if his work stopped at scurvy. But he was pointing at something far larger. He knew C was not just a “vitamin” but a two-electron donor that keeps collagen hydroxylated, stable, and conductive. Collagen, in his eyes was wire. Vitamin C was the sacrificial current that kept those wires aligned, allowing the body to conduct energy as well as hold itself together. That was the real meaning of his “electronic biology.” Gilbert Ling picked up that thread and made it radical. He rejected the idea of membrane pumps and showed instead that water inside cells is not bulk liquid but a polarized, structured medium ordered by proteins into an electronic continuum. This water could store charge, shape signals, and explain why life’s energy yield exceeds food inputs by orders of magnitude. Ling’s ideas were ridiculed for decades, but here’s the irony: MRI works because of him. Every scan depends on the different relaxation times of bound, structured water compared to bulk water. Clinical imaging quietly proves Ling right every single day. Now the pieces line up. Szent-Györgyi gave us the donor and the wire. Ling gave us the medium and the storage. Modern imaging shows the physiology at work. And evolution pushed the system further humans lost endogenous C, not as a suicide, but as a pivot. Melanin emerged as a renewable semiconductor, absorbing sunlight and generating electrons endlessly. Nitric oxide became light-gated, timed precisely to photons. The economy shifted from a liver drip of ascorbate to a field-based, light-driven charge flow. What looks like three separate stories—vitamin C, structured water, and MRI—are actually one continuous arc. The connective tissue of life is not calories but conductance. Szent-Györgyi saw the gatekeeper, Ling mapped the lattice, and modern physics gave us the instrument to confirm it. Once you see the ribbon, you can’t unsee it: biology is charge, stabilized by a vitamin, carried by collagen, stored in water, and renewed by light. Rick Cohen M.D.
“MrI wouldn't work if water didn't structure!!”
The electronic-biology perspective reframes interventions. Vitamin C is more than cofactor; it is an electron donor supporting conductive collagen. Structured intracellular water becomes a functional capacitor that stores and releases charge. MRI is not merely an imaging novelty but an empirical fingerprint of water states that validates the concept in clinical practice.
Operationally, this perspective directs attention to connective tissue conductance, light exposure, and redox provisioning as high-leverage levers. Collagen maintenance, copper handling, whole vitamin C complexes, hydration quality (including DDW where appropriate), and circadian light strategies become integrated priorities because they move the field more than calories alone ever could.
HRV and Recovery
Heart rate variability is valuable when interpreted as a contextual signal rather than a single score. Integrate HRV with breath-hold outputs, morning pH, orthostatic heart-rate changes, and sleep architecture to form actionable decisions about training density, amino acid timing, and recovery interventions.
Patterns over weeks are more meaningful than daily swings. Use moving averages and signal coherence to tune interventions. If HRV drifts while breath-hold and pH remain stable, suspect measurement noise or peripheral factors. If HRV and BHI both degrade, treat that as a terrain disruption requiring layered fixes: sleep/circadian, electrolyte and magnesium repletion, cooled temperature therapy, and reduced training load.