Dr. Rick's Insights
How Circadian Rhythms Won the Nobel Prize
Put simply, circadian rhythms are the internal 24 hour timing systems built into the human body over millions of years of evolution. They exist to keep us aligned with the natural rhythms of planet Earth, most notably the daily cycle of light and dark. These rhythms quietly organize how we feel and function across the day. They influence when we feel awake or sleepy, hungry or satisfied, focused or foggy. They shape our energy, mood, hormones, metabolism, immune function, and ability to repair and regenerate. Circadian rhythms are set by cues from our environment, known as zeitgebers or “time givers.”...
Could This Be Why Longevity Medicine Isn’t Working? - Dr. Rick Cohen, M.D.
Search trends around health and longevity are remarkably consistent. People aren’t asking how to live forever. They’re asking why they feel tired, foggy, inflamed, unmotivated, or fragile despite doing “everything right.” Queries like normal labs but feel sick, chronic fatigue with normal blood tests, why recovery is getting worse with age, and why biomarkers look good but I feel bad dominate health forums, Reddit threads, and clinical intake forms. The common thread is not confusion about biology. It’s frustration with results. But why? Modern longevity medicine produces more data than ever, yet outcomes for chronic decline, burnout, metabolic drift, and...
The Hidden Economics of Modern Supplements
And How Powder Became a Perfect Money Machine At some point, every supplement founder runs the numbers carefully enough to realize something uncomfortable: Most of the biggest “premium” supplement brands are not selling nutrition first.They are selling logistics efficiency. Once you see the mechanics, it becomes obvious why certain brands dominate, why their pricing always seems to work, and why others — even with better formulations — struggle to make the math close. This isn’t about ethics.It’s about physics. Powders and pills are the perfect fit. Both allow isolated cheap ingredients at scale, that weigh less and last longer. Let's...
Why Precision Medicine Often Fails in Chronic Disease: A Systems Perspective
Chronic disease is not primarily a parts problem. It is a dynamics problem. Precision without state estimation can increase fragility. By Dr. Rick Cohen The historical accident of modern medicine Modern clinical medicine was built to win acute battles. It evolved to manage infections, trauma, surgical complications, electrolyte collapse, and organ failure. Its workflows, lab testing, and pharmacology were optimized for short time horizons, relatively clear causal agents, and survival. The triumph of antibiotics reinforced a powerful assumption that still shapes practice: find the molecular cause, target it, and the problem resolves. That logic can be correct in acute regimes....