
How Does Caffeine Impact My Glucose?
Topic
Both as a supplement and a vice, caffeine is a daily staple for athletes. Since its removal from the WADA banned/monitored lists, it’s become ubiquitous in endurance culture—often paired with carbs straight after training at the local coffee spot.
Question
How does caffeine actually work, how fast does it hit, and what does it do to glucose and recovery on a CGM?
Caffeine is a CNS adenosine-receptor antagonist that can reduce perceived effort, increase motor unit firing, and shift substrate use (glycogen sparing). Effects can be felt in ~15 minutes and peak near 60 minutes, with long, genotype-dependent half-lives. Hydration myths are largely dispelled, but the metabolic signal remains complex.
Problem
Acute caffeine ingestion is associated with reduced insulin sensitivity and a transiently higher glycemic response versus decaf. In practice, that means your CGM may show higher glucose for the same carbohydrate load. There’s also the tolerance trap, sleep disruption from slow clearance, and the hidden risk of isolated, “spiky” caffeine forms. As framed here: isolated caffeine is the WROST type of caffeine for your health—an unhealthy energy spike with a long-term tax on vessels, brain, and metabolism.
Translation for terrain tracking: short-term ergogenesis versus long-term autonomic, glycemic, and sleep costs if you use the wrong form, dose, or timing.
Solution
Use caffeine as a precise tool, not a blunt dose. Test on your CGM. Keep timing 45–60 minutes pre-effort for peak CNS benefit; avoid late-day use if you’re a slow metabolizer. Pair with real-food polyphenols and L-theanine to smooth the curve; dose in the moderate zone (~3–6 mg/kg) when you truly need performance, not by habit. When recovering, pair modest caffeine with carbohydrate to assist glycogen resynthesis after morning sessions; skip it later if sleep is the priority.
Prefer whole-matrix caffeine over isolates. Coffee with supportive botanicals and nitrate-rich co-factors shifts the signal away from “spike and crash” toward steadier autonomic tone and substrate handling. Use your CGM to compare: same meal, with and without your coffee protocol.
Brand Solution
This is why we created the caffeine-perception-shifting performance coffee called UNBEETABREW. Give it a try with your CGM and note the effects. Do you perform better and get healthier than after using regular coffee alone?
UNBEETABEW is boosted with beet juice powder for more endurance, detoxification and blood pressure support, organic and medium caffeine beans for a stable healthy energy burn, green tea extract for weight loss, L-Theanine for focus and a 5 mushroom stress busting blend. It's without a doubt the most intensely upgraded coffee on earth!
Try UNBEETABREWReady to shift your coffee-for-health-and-performance paradigm into another dimension? Test it. Track it. Keep what improves your terrain.
Mechanism, Timing, and Metabolism (for the curious)
Numerous studies have shown mixed-metabolism performance benefits. Caffeine competitively blocks adenosine to reduce perceived effort and pain, may alter energy substrate use (glycogen sparing), and increase motor unit firing for more sustainable contraction. Effects are perceived within ~15 minutes, peak near ~60, and can persist due to half-lives of 3–10 hours depending on genetics and habituation.
One proposed metabolic benefit is increased lipolysis and free fatty acid availability, reducing glycogen reliance at ~80% VO2max. Co-ingestion with carbohydrate can increase exogenous carbohydrate oxidation rates; very high doses (e.g., 5 mg/kg/h in lab protocols) are not practical for most athletes. Strength benefits are less consistent than endurance benefits, with significant inter-individual variability and a research bias toward male participants.
On recovery, modest caffeine paired with carbohydrate may enhance glycogen resynthesis post-exercise, but late-day dosing can harm sleep—arguably the most important recovery lever.
References
Yang A, Palmer AA, de Wit H. Psychopharmacology (Berl). 2010;211(3):245-257. doi:10.1007/s00213-010-1900-1
Rivers WH, Webber HN. J Physiol. 1907;36(1):33-47. doi:10.1113/jphysiol.1907.sp001215
Pickering C, Kiely J. Sports Med. 2018;48(1):7-16. doi:10.1007/s40279-017-0776-1
Lopez-Gonzalez LM. et al. J Int Soc Sports Nutr. 2018;15:60. doi:10.1186/s12970-018-0267-2
Davis JK, Green JM. Sports Med. 2009;39:813–832.
San Juan AF. et al. Nutrients. 2019;11:2120. doi:10.3390/nu11092120
Salinero JJ. et al. Res Sports Med. 2019;27:238–256.
Mielgo-Ayuso J. et al. Nutrients. 2019;11:440.
Tarnopolsky MA. Appl Physiol Nutr Metab. 2008;33(6):1284-9.
Graham TE. Sports Med. 2001;31(11):785-807.
Institute of Medicine… https://www.ncbi.nlm.nih.gov/books/NBK223808/
Killer SC. et al. PLoS One. 2014;9(1):e84154.
Armstrong LE. et al. Int J Sport Nutr Exerc Metab. 2005;15(3):252-65.
Goldstein ER. et al. J Int Soc Sports Nutr. 2010;7:5
Ivy JL. et al. Med Sci Sports. 1979;11:6–11.
Van Nieuwenhoven MA. et al. J Appl Physiol. 89(3):1079-85, 2000.
Yeo SE. et al. J Appl Physiol. 2005;99(3):844-50. doi:10.1152/japplphysiol.00170.2005
Shi X. et al. Nutr J. 2016;15:103. https://doi.org/10.1186/s12937-016-0220-7
Suchomel TJ. et al. Sports Med. 2018;48:765–785.
Thibault V. et al. J Sports Sci Med. 2010;9:214–223
Loureiro LMR. et al. Int J Sport Nutr Exerc Metab. 2018;28(3):284-293.