How To Use BPC-157

By Dr. Rick Cohen • Updated September 17, 2025

BPC 157 has been around for a little while and does have some great research behind it. BPC 157 has seen to enhance tissue healing, reduce inflammation, protect the gastrointestinal system, promote muscle and tendon repair, exert neuroprotective effects, and demonstrate a favorable safety profile makes it a promising tool in regenerative medicine. Further research is needed to fully understand its mechanisms of action and explore its potential applications in various conditions. Designed to help heal and rebuild, FundAminos, is focusing on high protein health which essential for any healing treatment. But, as with any treatment, please do under the supervision of a doctor, or consult with our very own Dr. Cohen M.D., for safety and optimal results. Check out other injections for pain here

BPC-157: A Regenerative Peptide Worth Knowing About

BPC-157 has been gaining attention among those seeking advanced recovery options. The protocol involves retrieving a small vial from refrigeration, drawing a precise amount using an insulin syringe, and administering it subcutaneously at various sites around the body. Users report remarkable results with this peptide.

Reported Benefits of BPC-157

Those who have used BPC-157 often report:

Significant reduction in digestive inflammation triggered by travel, stress, and competition

Resolution of chronic elbow pain conditions including medial epicondylitis

Unexpectedly rapid healing of hamstring tears and similar injuries that typically require extended recovery

The effectiveness of this peptide is so impressive that increased regulatory oversight may occur in coming years.

Understanding BPC-157

Researchers have been investigating BPC-157 since the early 1990s. This peptide has demonstrated impressive tissue regeneration capabilities across multiple body systems. It can be administered orally, via subcutaneous injection, or intramuscularly, with minimal reported adverse effects.

Scientific literature suggests BPC-157 may:

Accelerate tendon and ligament healing by enhancing cellular proliferation and migration

Improve tendon-to-bone connection healing, potentially offering alternatives to certain surgical interventions

Protect the gastrointestinal tract from damage caused by non-steroidal anti-inflammatory medications

Support rapid repair in inflammatory bowel conditions

Enhance healing of periodontal tissues

Counter healing delays typically associated with corticosteroid use

Support faster bone regeneration following injury

What makes BPC-157 particularly interesting is its stability in digestive environments and its healing effects throughout the gastrointestinal system, making it a compelling option for those dealing with persistent gut issues, joint pain, or muscle injuries.

Sourcing BPC-157

Currently, BPC-157 can be purchased from various online peptide retailers, though it's important to note it's sold as a "research compound" not intended for human consumption. Navigating these suppliers requires research and discretion.

Those considering BPC-157 will also need to acquire:

Insulin syringes (1ml capacity with 28G, ½" needles)

Bacteriostatic water (30ml)

Alcohol prep pads

Compared to many regenerative medicine treatments available in clinical settings, this approach represents a more accessible option for supporting recovery and maintaining joint and muscle health.

Preparation Protocol

BPC-157 typically arrives as a lyophilized (freeze-dried) powder requiring reconstitution before use:

Remove the protective caps from both the BPC-157 vial and bacteriostatic water bottle

Disinfect the rubber stoppers using alcohol wipes and allow to air dry

Carefully introduce 3ml of bacteriostatic water into a 5mg BPC-157 vial, taking care not to directly spray the powder

Store appropriately—room temperature keeps it stable for weeks, refrigeration for months, and freezing for up to two years

BPC-157 is particularly sensitive. Users should avoid agitation, heat exposure, or rushing the reconstitution process to maintain efficacy.

For those struggling with persistent injuries or digestive concerns, BPC-157 may offer an intriguing option. However, thorough research and careful consideration are essential before beginning any self-administered peptide protocol.

Before and after reconstitution, keep your BPC-157 away from UV rays, sunlight, and heat. It will remain stable at room temperature for up to ten weeks, but for the best storage and results, you should store in your refrigerator, in which case it will stay stable for up to six months. It will stay stable in a freezer for up to two years.

BPC-157 Dosage Guidelines and Administration Methods

Recommended Dosage

Research on BPC-157 indicates effectiveness when administered at doses ranging from 1-10 micrograms per kilogram of body weight once daily. For most individuals, this translates to a daily dose between 200-800mcg. Some users report optimal results when dividing the daily amount into two separate doses of 250-350mcg, totaling 500-700mcg per day.

This wide range in dosage recommendations creates flexibility for individual needs, though it can also cause confusion for new users.

Clinical Experience

Many individuals using BPC-157 for conditions like medial epicondylitis (commonly known as golfer's elbow or climber's elbow) have found success with a protocol of 250mcg administered subcutaneously near the affected area. Some users alternate between treatment sites when addressing multiple areas, such as injecting one elbow one day and the other elbow the next day, for a two-week treatment course. Many report complete resolution of symptoms within this timeframe.

While BPC-157 typically shows minimal side effects at standard dosages, higher doses may produce temporary symptoms. For example, accidental administration of 2500mcg (10 times the intended dose) has been reported to cause approximately four hours of mild irritability and mood changes, likely resulting from an elevated cortisol response to the significant dose. These effects generally subside without lasting issues.

Administration Methods

BPC-157 functions systemically throughout the body, offering flexibility in administration methods:

Subcutaneous Injection

This is often preferred as a less painful method where the solution is injected just beneath the skin, ideally as close to the injured area as possible. The process involves:

Pinching an area of skin near the treatment site

Inserting the needle into the pinched skin

For difficult-to-pinch areas (like elbows), using an angled approach to slip the needle under the skin or seeking assistance

Intramuscular Injection

While more uncomfortable, this method involves injecting directly into the muscle near the injury site.

Oral Administration

For those avoiding injections, oral use can be effective:

Spray the solution slowly into the mouth

Hold in the mouth for 90-120 seconds

Swallow

Important Safety Protocols

Regardless of administration method, proper sanitization is essential:

Always clean the rubber stopper of the vial with an alcohol swab before drawing the solution
Always disinfect the injection site with an alcohol swab before administration
Follow proper subcutaneous injection techniques as demonstrated in instructional videos

These guidelines help users administer BPC-157 safely while maximizing its potential therapeutic benefits for various injuries and conditions.

Here's a video that shows you the basics of subcutaneous injection: watch here

Intramuscular Injection Technique for BPC-157

Intramuscular (IM) injections represent the most challenging administration method for BPC-157. This approach requires more precision and typically causes more discomfort than subcutaneous methods, but may provide benefits for certain injury types.

Essential Sanitation Protocols

As with all injection methods, strict hygiene practices are critical:

Thoroughly disinfect the vial's rubber stopper with an alcohol swab before drawing the solution
Clean the injection site completely with an alcohol swab and allow to dry

Injection Procedure

Unlike subcutaneous administration, intramuscular injection requires:

Inserting the entire needle through the skin
Penetrating into the muscle tissue
Delivering the solution as close to the injury site as possible

For deep tissue injuries like hamstring tears, this direct approach may contribute to accelerated healing. Many users report that despite the momentary discomfort, the rapid recovery benefits make the procedure worthwhile.

Managing Discomfort

The pain associated with intramuscular injections can be mitigated through:

Distraction techniques or visualization
Focusing on positive outcomes
Using proper technique to minimize unnecessary trauma
Taking slow, deep breaths during administration

Learning Proper Technique

For those unfamiliar with intramuscular injections, instructional videos demonstrating proper technique are valuable resources before attempting self-administration. These visual guides help ensure correct needle angle, proper depth, and appropriate injection speed.

While more uncomfortable than other administration methods, intramuscular BPC-157 injections may provide enhanced delivery to certain injury sites, potentially contributing to faster tissue regeneration and recovery.

Watch here

BPC-157 Administration Techniques and Treatment Duration Guide

Optimizing Injection Effectiveness

For both subcutaneous and intramuscular BPC-157 injections, absorption and effectiveness can be enhanced through proper technique:

After administering the injection, gently massage the area for 30-60 seconds
Focus massage around both the injection site and the painful area
This technique helps work the peptide more thoroughly into the targeted tissues
Massage promotes better distribution and potentially more complete absorption

Treatment Duration Guidelines

Treatment duration with BPC-157 varies based on the specific condition being addressed:

Joint and Tendon Injuries

Conditions like medial epicondylitis (golfer's/climber's elbow) often respond well to a treatment protocol of:

250mcg subcutaneous injections
Administered on alternating days between affected areas
Typically showing significant improvement within two weeks

Muscle Strains

For muscular injuries such as hamstring strains:

Daily intramuscular injections of 250mcg directly near the injury site
Complete healing often reported within 7-10 days
Pain reduction typically begins within the first few days of treatment

Digestive Applications

Oral administration for gastrointestinal support:

250mcg administered orally for 7+ days
Users report sensations similar to protective digestive aids
Benefits include reduced digestive discomfort, decreased bloating, and less post-meal gastrointestinal distress
May benefit those with irritable bowel issues or gut inflammation

Recommended Protocols

Based on available human studies, a general protocol involves:

Administration for up to four weeks
Followed by a two-week rest period
Repeat cycles typically unnecessary unless reinjury occurs
Most users report significant improvement within 1-2 weeks for localized injuries

Availability Considerations

Despite its therapeutic potential, BPC-157 remains relatively unknown in conventional medical settings for several reasons:

As a naturally occurring gastric peptide, it has limited patentability
Pharmaceutical companies have minimal financial incentive for development
Not currently marketed to medical professionals through traditional channels
Not available as an FDA-regulated drug for human use

Athletic Competition Considerations

For competitive athletes concerned about regulatory compliance:

BPC-157 is not currently listed among prohibited "peptide hormones, growth factors, related substances, and mimetics" by major sports governing bodies like USADA or WADA
Regulatory status may change in the future
Athletes should monitor updates to prohibited substance lists

Research Limitations

When considering BPC-157 use, it's important to acknowledge:

Long-term human studies remain limited
Most positive evidence comes from shorter-term trials
No significant adverse reactions have been documented in human clinical trials to date

For those dealing with persistent injuries, inflammatory conditions, or digestive issues, BPC-157 represents a potentially valuable recovery tool, though users should maintain awareness of evolving research and regulatory status.

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