Metabolic & Longevity Strategies with Dr. Rick Cohen, M.D.

Dr. Rick Cohen, M.D. is a leading authority in the fields of nutrition, sports performance, and longevity medicine. He received his undergraduate degree in Biomedical Engineering from Duke University and his medical degree from Hahnemann Medical University. Over the past 20 years, he has created innovative health and performance protocols and specially-formulated nutritional products to bring thousands of sport enthusiasts and elite athletes to higher levels of performance.

In this episode we discuss

• Toxins and poor metabolic health are the biggest inhibitors of longevity

• Toxins usually include xenoestrogens, iron, toxic thoughts and emotions,  glyphosate, metals

• The biggest bottleneck in metabolic health is in the mitochondrial electron transport chain, and specifically Cytochrome C Oxidase (complex 4)

• Bound iron stuck in the spleen and liver are a big driver of free radical damage and aging

• Sometimes for anemic individuals a half unit blood draw can reboot the recycling system to correct hemoglobin levels

• In Australia, there’s a clinic using MRI scans of liver and spleen to determine iron saturation. They don’t see correlation between Ferritin levels and iron saturation of these tissues.

• In Dr. Rick’s analysis of longevity research, the greatest driver of lifespan and health span is the ability of the body to regenerate

• Fasting lactate is a great marker of metabolic health. Low is best.

• Circadian temperature is also a great marker of metabolic health as it tracks thyroid function. It should be highest during the day and lowest at night.

• Calorie restriction, fasting and low carb diets also reduce metabolism, increase lactate and decrease body temperature

• VO2 max if not a good measure of longevity. The important metric is end-title CO2, the amount of CO2 you exhale, which is a direct metabolite of good mitochondrial function

• If optimal total testosterone, but mid-low free testosterone likely iron overload. If low total testosterone, the issue is metabolic

• Elevated SHBG usually caused by either xenoestrogens, iron overload, or low carb diets

• Stress/cortisol depletes progesterone and increases estrogen

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