The BEST Supplements To Build Muscle & Bone During Perimenopause by Dr. Doug Lucas
In this article, we will delve into the crucial relationship between muscle strength, supplements, and the prevention of osteoporosis. Dr. Doug Lucas will guide us through the potential benefits of FundAminos Essential Amino Acids and Branched-Chain Amino Acids for building muscle during perimenopause and post-menopause, shedding light on their impact on bone density preservation. Watch the video below!
Amino acid supplements play a crucial role in increasing lean body mass and stimulating growth factors in older women. As individuals age, there is a natural decline in muscle mass and strength, leading to a condition known as sarcopenia. This process can be further exacerbated in postmenopausal women due to hormonal changes.
Amino acids are the building blocks of protein, which is essential for muscle growth, repair, and maintenance. By supplementing with amino acids, particularly essential amino acids such as leucine, isoleucine, and valine, older women can effectively support muscle protein synthesis and counteract the muscle loss associated with aging.
Furthermore, amino acids promote the production of growth factors such as insulin-like growth factor 1 (IGF-1) and testosterone, which are key regulators of muscle growth and repair. By stimulating these growth factors, amino acid supplements can help older women increase muscle mass, improve muscle function, and enhance overall strength and physical performance.
In conclusion, incorporating amino acid supplements into the diet of older women can be a valuable strategy for preserving lean body mass, promoting muscle growth, and supporting overall health and vitality.
Amino acid supplementation has been shown to have significant beneficial effects on muscle mass, strength, and physical function in the elderly. Amino acids are the building blocks of proteins, which play a crucial role in muscle synthesis and repair. By supplementing with amino acids, older individuals can support their muscle health and function, ultimately improving their overall physical performance and quality of life. Studies have demonstrated that amino acid supplementation can help prevent muscle loss, increase muscle protein synthesis, and enhance muscle strength in the elderly. Additionally, amino acids such as leucine have been found to stimulate muscle protein synthesis and promote muscle recovery after exercise. Therefore, incorporating amino acid supplementation into the diet of older adults can be a valuable strategy for maintaining muscle mass, strength, and physical function as they age.
Lean body mass (LBM) increased during the study (p = 0.038). At week 12, the average increase in LBM was 1.14 ± 0.36 kg (p < 0.05 vs baseline), whereas at week 16, the increase was 0.60 ± 0.38 kg (NS vs baseline). The lower extremity strength measure score (sum of individual knee flexors and extensors 1-repetition maximum, n = 10) was 127.5 ± 21.8 kg at baseline, and average increase during the study was 22.2 ± 6.1% (p < 0.001). Improvements were also observed in usual gait speed (p = 0.002), timed 5-step test (p = 0.007), and timed floor-transfer test (p = 0.022).
Nutritional supplements containing oral amino acid mixtures have shown promising results in increasing whole-body lean mass and improving insulin sensitivity in older women. Studies have demonstrated the effectiveness of these supplements in promoting muscle protein synthesis and supporting overall metabolic health in this specific demographic. By incorporating these oral amino acids into their daily regimen, older women can experience significant improvements in both body composition and metabolic function, ultimately enhancing their overall health and well-being.
Decreases in whole-body lean mass can cause sarcopenia, a disease frequently found in the elderly. This condition is frequently associated with frailty and disability in aging as well as the onset and progression of several geriatric syndromes. Sarcopenia therefore must be managed with multidimensional approaches that include physical training, nutritional support, and metabolic and anabolic treatment. The purpose of our study was to assess the effect of an orally administered special mixture of amino acids (AAs) in elderly subjects with reduced lean body mass and sarcopenia. A randomized, open-label, crossover study was conducted in 41 elderly subjects (age range: 66-84 years) with sarcopenia, assigned to 2 distinct treatments (AAs and placebo). All subjects had normal body weight (body mass index within 19-23). The AA treatment consisted of 70.6 kcal/day (1 kcal = 4.2 kJ) of 8 g of essential AA snacks, given at 10:00 am and 5:00 pm. Lean mass was measured with dual-energy x-ray absorptiometry in leg, arm, and trunk tissues. Significant increases in whole-body lean mass in all areas were seen after 6 months and more consistently after 18 months of oral nutritional supplementation with AAs. Fasting blood glucose, serum insulin, and homeostatic model assessment of insulin resistance (an index of insulin resistance) significantly decreased during AA treatment. Furthermore, a significant reduction in serum tumor necrosis factor-alpha (TNF-alpha) and a significant increase in both insulin-like growth factor-1 (IGF-1) serum concentrations and in the IGF-1/TNF-alpha ratio were also found. No significant adverse effects were observed during AA treatment. These preliminary data indicate that nutritional supplements with the oral AA mixture significantly increased whole-body lean mass in elderly subjects with sarcopenia. The improvement in the amount of whole-body lean mass could be linked to increased insulin sensitivity and anabolic conditions related to IGF-1 availability.
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